Removal of Tropomyosin Overlap Modifies Cooperative Binding of Myosin S-1 to Reconstituted Thin Filaments of Rabbit Striated Muscle
نویسندگان
چکیده
منابع مشابه
Fragments of Rabbit Striated Muscle a - Tropomyosin
The interactions of a variety of large fragments of rabbit skeletal muscle a-tropomyosin, prepared as previously described, with troponin-T and a soluble tropomyosin-binding fragment of troponin-T (CB1) have been investigated by affinity chromatography and gel filtration. No specific interactions between NHz-terminal fragments encompassing residues 1-189 with troponin, troponin-T, or CB1 immobi...
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Cooperative activation of striated muscle by calcium is based on the movement of tropomyosin described by the steric blocking theory of muscle contraction. Presently, the Hill model stands alone in reproducing both myosin binding data and a sigmoidal-shaped curve characteristic of calcium activation (Hill TL (1983) Two elementary models for the regulation of skeletal muscle contraction by calci...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1989
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)81818-x